Sun lamps and tanning beds are off limits, too. Stacy Wiegman, PharmD People who have had asthma, epilepsy or other seizure disorders, kidney problems or liver problems w More Answers What happens if I miss a dose of ciprofloxacin? Stacy Wiegman, PharmD Don't worry, there's no cause to be upset. Simply take the dose you missed as soon as you rememb More Answers How soon after taking ciprofloxacin will my symptoms improve?
Stacy Wiegman, PharmD You should begin to notice some easing of your symptoms a few days after you start taking ciprof More Answers Can I use ciprofloxacin if I'm taking other medications? These photosensitizers, or chromophores, possess a unique ability to absorb ultraviolet light at the particular wavelength spectrum found in sunlight or artificial sunlight UVA and UVB. This ability, however, is not the problem. Instead the unique structural characteristics of these medicationssuch as halogenated aromatic rings or alternating single and double bondslead to the destabilization of their chemical structure and a transfer of energy that induces a buildup of damaging compounds in the skin.
It is important to note that not all people will develop a reaction to a photosensitizer. Fair-skinned people may be more susceptible, much as they are to sun damage in general.
The two distinct types of drug-associated photoreactions are phototoxic and photoallergic reactions. In the less common photoallergic reactions, the destabilized drug structure forms a complex called a hapten that prompts a localized immune response. White blood cells lymphocytes and eosinophils invade the skin and release immune mediators that cause increased leakage in the local veins, redness erythema and swelling edema. In a few documented cases, even areas unexposed to the sun can become affected.
Photoallergic reactions are usually delayed in onset and appear sometime after 24 hours of drug administration as a superficial dermatitislike reaction.
These reactions may occur even after only one dose. Phototoxic reactions, however, manifest as a more severe burn reaction and may arise within a few hours after the drug is taken. They usually involve a higher drug dosage than photoallergic reactions do.
In these cases, destabilization of the drug structure results in an accumulation of free radicals and localized cell damage. This effect is more extensive than the superficial photoallergic reaction and leads to cell damage at multiple levels of the dermis and epidermis.
But Dr. If you find yourself getting red after a short time in the sun, seek cover. You could end up with additional symptoms such as blisters and itchiness if you stay out unprotected. Of course, the best way to treat photosensitivity and prevent these side effects is with proper sun protection.
That means covering up, avoiding being outside between 10 a. Another option for people who know they are going to be outside for long periods of time, but need to take a specific medication that increases their sun sensitivity, is to discuss alternatives with their doctor.
Skip to main content Search for a topic or drug. Shedding light on medications that increase sun sensitivity. By Sarene Leeds Jul.
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